Sidhartha Tan

Dr Sidhartha Tan is presently Leslie Helppie Endowed Professor in Urban Health, Department of Pediatrics, Wayne State University School of Medicine. His research focuses on Big Data analytics in neonatal intensive care, advanced neonatal nursing, olfactory memory testing, neuroimaging, neuroprotective drugs, and neonatology education. His basic science research explores mechanisms of brain injury in newborns, with his lab continuously funded since 1992, currently holding three NIH R01 grants. Using rabbit models of cerebral palsy, his work investigates hypoxia-ischemia at various gestational ages, mimicking acute placental insufficiency. His studies examine free radicals, reactive oxygen and nitrogen species, grey and white matter injury, oligodendroglial damage, brain cell death, and epigenetics. He has also pioneered MRI biomarkers to predict motor deficits in foetuses and developed the first transgenic knockout and knock-in rabbit models to study brain injury. He has authored over 75 publications and currently serves on the editorial board of Developmental Neuroscience.