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# PREMSTEM

The brain injury in the premature born infant: stem cell regeneration research network

## Sitemaps

- [XML Sitemap](https://www.premstem.eu/sitemap.xml): Contains all public & indexable URLs for this website.

## Posts

- [PREMSTEM research lays the groundwork for future stem cell clinical trials](https://www.premstem.eu/2026/04/10/premstem-research-lays-the-groundwork-for-future-stem-cell-clinical-trials/) - The PREMSTEM project has explored how human mesenchymal stem cells could help to repair brain injury in children born preterm.
- [Illustrating two families' stories of preterm birth](https://www.premstem.eu/2025/10/14/growing-together-illustrated-story/) - Alongside our scientific work, communicating with the wider world about the topics of preterm birth and brain injury has been one of our focuses in PREMSTEM. Growing Together – A Shared Journey from the NICU to Now is an illustrated story created by members of the consortium and the PCAB in collaboration with professional illustrators. Sophia
- [Global experts converge in Barcelona for the PREMSTEM Conference: Research into neonatal brain repair](https://www.premstem.eu/2025/06/17/premstem-conference-summary/) - From 13 to 15 May 2025 the PREMSTEM consortium was joined in Barcelona by members of the scientific community, medical professionals, and parent and patient representatives from Europe, North America and Australia for our final conference. The conference theme ‘Research into neonatal brain repair’ set the scene to present PREMSTEM’s scientific findings to the public
- [2025 Annual meeting](https://www.premstem.eu/2025/06/16/2025-annual-meeting/) - The PREMSTEM team met in Barcelona on 12 and 13 May 2025 for the annual in person meeting, held just before the project's public conference. Invited to the meeting were consortium partners as well as members of our scientific advisory boards. We shared our latest research progress and findings as well as updates related
- [Manon Benders](https://www.premstem.eu/2025/05/11/manon-benders/) - Manon Benders Dr Manon BendersPediatrician-neonatologistWilhelmina Children’s Hospital, UMC Utrecht (The Netherlands) Session: From pre-clinical work to an approved therapy - Wednesday 14 May (10.30am-12pm​) Manon Benders is a neonatologist with an interest in neonatal neurology. She is Professor in Neonatology at the Wilhelmina Children’s Hospital, UMC Utrecht. Her work focuses on improving long-term outcomes in
- [Daan Ophelders](https://www.premstem.eu/2025/05/07/daan-ophelders-2/) - Daan Ophelders Dr Daan OpheldersAssistant Professor, Laboratory of PediatricsMaastricht University (The Netherlands) Session: Learnings from co-creation: involving external stakeholders in research - Thursday 15 May (8.30-10am​) Daan Ophelders is an Assistant Professor at Maastricht University’s Faculty of Health, Medicine and Life Sciences, specialising in translational neonatology. His research focuses on the inflammatory response in foetal
- [Caroline de Theije](https://www.premstem.eu/2025/05/06/caroline-de-theije-2/) - Caroline de Theije Dr Caroline de TheijeAssistant ProfessorUMC Utrecht (The Netherlands) Session: Alternatives and adjuncts to stem cells - Wednesday 14 May (3.30-5pm) Caroline de Theije is Assistant Professor at the Department for Developmental Origins of Disease at University Medical Center Utrecht, The Netherlands. She has a background in medical biology. She graduated from the
- [Martina Gabrielli](https://www.premstem.eu/2025/05/02/martina-gabrielli/) - Martina Gabrielli Dr Martina GabrielliResearch FellowNational Research Council of Italy (CNR) Institute of Neuroscience (Italy) and currently at Nottingham Trent University (UK) Session: In vitro studies of stem cell activities - Thursday 15 May (10.30am-12pm) Martina Gabrielli is currently a Research Fellow at Nottingham Trent University (UK) and recipient of a BBSRC Fellowship (UKRI) for
- [Tamara Yawno-Fegan](https://www.premstem.eu/2025/05/02/tamara-yawno-fegan/) - Tamara Yawno-Fegan Dr Tamara Yawno-FeganSenior Research FellowHudson Institute of Medical Research and Monash University (Australia) Session: Using large animal translational models and how to do it better - Wednesday 14 May (8.30-10am) Tamara Yawno is a renowned developmental neuroscientist with over 17 years of experience investigating neurodevelopment in large animal models of cerebral palsy. Her
- [Cindy Bokobza](https://www.premstem.eu/2025/04/24/cindy-bokobza-2/) - Cindy Bokobza Dr Cindy BokobzaHead Scientist at MayInserm U1141 (France) Session: From pre-clinical work to an approved therapy - Wednesday 14 May (10.30am-12pm​) Cindy Bokobza is a perinatal neuroscientist and head scientist at May, a mission-driven health tech startup. She has a background in translational research, with experience in France, the USA, and Portugal. Cindy
- [William Dawes](https://www.premstem.eu/2025/04/24/william-dawes/) - William Dawes Dr William DawesAcademic Paediatric NeurosurgeonConsultant Paediatric Neurosurgeon, Oxford University Hospital (UK); Honorary Associate Professor, Institute of Child Health, University College London (UK) Session: Learnings from co-creation: involving external stakeholders in research - Thursday 15 May (8.30-10am​) William Dawes is an academic paediatric neurosurgeon from Oxford University Hospital. He was awarded his PhD from
- [András Lakatos](https://www.premstem.eu/2025/04/24/andras-lakatos/) - András Lakatos Dr András LakatosAssociate Professor of Neurobiology and Neurology Department of Clinical Neurosciences, University of Cambridge Session: Novel and innovative approaches to screening - Tuesday 13 May (2-3.30pm) András Lakatos is Associate Professor of Neurology and Neurobiology at the University of Cambridge and leads a research laboratory in the Department of Clinical Neurosciences. Over
- [Md Munnaf Hossen](https://www.premstem.eu/2025/04/22/md-munnaf-hossen/) - Md Munnaf Hossen Md Munnaf HossenPhD candidate, School of Health and Biomedical SciencesRMIT University (Australia)Session: Cell based therapies in animal studies - Wednesday 14 May (1.30-3pm) Md Munnaf Hossen is a PhD candidate at RMIT University, Australia working with Dr Rosita Zakaria and Dr Bobbi Fleiss. He is investigating the effects of perinatal brain injury
- [Jessica Dubois](https://www.premstem.eu/2025/04/14/jessica-dubois/) - Jessica Dubois Dr Jessica DuboisResearcher Inserm, NeuroDiderot unit, NeuroSpin center (France) Session: Imaging modalities - Thursday 15 May (12.30-2pm) Jessica Dubois has been a researcher in neuroscience at Inserm (France) since 2009. She heads the inDEV team (Imaging of Neurodevelopmental Phenotypes) at the NeuroDiderot unit, between the Robert-Debré paediatric hospital (Paris) and the NeuroSpin center
- [Nicola Pelizzi](https://www.premstem.eu/2025/04/14/nicola-pelizzi/) - Nicola Pelizzi Dr Nicola PelizziGlobal Project LeaderChiesi Farmaceutici (Italy) Session: Learnings from co-creation: involving external stakeholders in research - Thursday 15 May (8.30-10am​) • Degree and PhD in Chemical Sciences in 1998.• From 1998 to 2007, R&D Senior Scientist in Analytical Chemistry Department at Chiesi Farmaceutici.• From 2008 to 2011, R&D Project Manager at Chiesi
- [Silvia Coco](https://www.premstem.eu/2025/04/14/silvia-coco/) - Silvia Coco Dr Silvia CocoSenior ResearcherUniversity of Milano Bicocca (Italy) Session: Alternatives and adjuncts to stem cells - Wednesday 14 May (3.30-5pm) Silvia Coco is a tenured researcher at the Department of Medicine and Surgery, University of Milano-Bicocca, with a degree in Biological Sciences and expertise in pharmacology and neuroscience. Her research investigates innovative therapeutic
- [Roosmarijn Vandenbroucke](https://www.premstem.eu/2025/04/09/roosmarijn-vandenbroucke/) - Roosmarijn Vandenbroucke Professor Roosmarijn VandenbrouckeHead of the Barriers in Inflammation LabFull professor at Ghent UniversityGroup leader at VIBDepartment of Biomedical Molecular Biology, Ghent University, Ghent (Belgium)Center for Inflammation Research, VIB, Ghent (Belgium) Session: Alternatives and adjuncts to stem cells - Wednesday 14 May (3.30-5pm) Roosmarijn Vandenbroucke is head of the Barriers in Inflammation at the
- [Bernard Thébaud](https://www.premstem.eu/2025/04/08/bernard-thebaud/) - Bernard Thébaud Dr Bernard ThébaudSenior Scientist, Regenerative Medicine, Ottawa Hospital, Research Institute & CHEO Research Institute; Neonatologist, Division of Neonatology, The Ottawa Hospital and the Children’s Hospital of Eastern Ontario; Professor of Pediatrics, University of Ottawa; Partnership Research Chair in Regenerative Medicine, University of Ottawa; Tier 1 Canada Research Chair in Lung Stem Cell Biology
- [Elisabet Farga Carrera](https://www.premstem.eu/2025/04/08/elisabet-farga-carrera/) - Elisabet Farga Carrera Elisabet Farga CarreraPresident/founderSom Prematurs (Spain) Session: Learnings from co-creation: involving external stakeholders in research - Thursday 15 May (8.30-10am​) Elisabet Farga Carrera is the president and founder of the Premature Babies Association of Catalonia - Som Prematurs - and a mother of premature twins. She is deeply involved in co-creation forums, including
- [Nicole Labusek](https://www.premstem.eu/2025/04/08/nicole-labusek/) - Nicole Labusek Dr Nicole LabusekPostdoctoral researcher Department of Paediatrics I, Neonatology and Experimental perinatal Neurosciences, Centre for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, University Duisburg-Essen, 45147 Essen (Germany) Session: Cell based therapies in animal studies - Wednesday 14 May (1.30-3pm) Nicole Labusek is a neuroscientist specialising in neonatal brain injury and cell-based
- [Valéry van Bruggen](https://www.premstem.eu/2025/04/03/valery-van-bruggen-2/) - Valéry van Bruggen Valéry van BruggenPhysician – Clinical Investigator Department of Pediatrics, Maastricht University Medical Center+, MosaKids Children’s Hospital, Maastricht (The Netherlands) Session: Imaging modalities - Thursday 15 May (12.30-2pm) Valéry van Bruggen studied Biomedical Sciences at the Rijksuniversiteit Groningen followed by the research master physician-clinical investigator. Since 2020 she has been working with the
- [Stefanie Obst](https://www.premstem.eu/2025/04/02/stefanie-obst/) - Stefanie Obst Stefanie ObstPhD studentDepartment of Paediatrics I, Neonatology and Experimental perinatal Neurosciences, Centre for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen (Germany) Session: Novel and innovative approaches to screening - Tuesday 13 May (2-3.30pm) Stefanie Obst completed both her Bachelor's and Master's degrees in Molecular Biology with a focus on experimental research
- [Meray Serdar](https://www.premstem.eu/2025/04/02/meray-serdar/) - Meray Serdar Dr Meray SerdarPostdoctoral Researcher Department of Pediatrics I/Neonatology & Experimental Perinatal Neurosciences, University Hospital Essen (Germany)Session: Cell based therapies in animal studies - Wednesday 14 May (1.30-3pm) Meray Serdar studied biochemistry and completed a master's degree in electrophysiology. In 2012, she began her PhD at the Department of Pediatrics I/Neonatology & Experimental Perinatal
- [Courtney McDonald](https://www.premstem.eu/2025/04/02/courtney-mcdonald/) - Courtney McDonald Dr Courtney McDonaldNHMRC EL2 Investigator The Ritchie Centre, Hudson Institute of Medical Research (Australia) Session: Using large animal translational models and how to do it better - Wednesday 14 May (8.30-10am) Courtney McDonald is an NHMRC EL2 Investigator and leads the Cell Therapies and Neuroinflammation Research Group at The Ritchie Centre, Hudson Institute
- [Sanne Claassen](https://www.premstem.eu/2025/03/28/sanne-claassen/) - Sanne Claassen Dr Sanne ClaassenPhD studentDepartment of Pediatrics, Maastricht University Medical Center+, MosaKids Children’s Hospital, Maastricht (The Netherlands) Session: Using large animal translational models and how to do it better - Wednesday 14 May (8.30-10am) Sanne Claassen is a medical doctor and PhD student in the Pediatric Department at Maastricht University, the Netherlands. The paediatric
- [Enrique Conches](https://www.premstem.eu/2025/03/28/enrique-conches/) - Enrique Conches Enrique ConchesCreative Innovation LeaderFounder, Punk Design (Spain) Session: Learnings from co-creation: involving external stakeholders in research - Thursday 15 May (8.30-10am​) Enrique Conches is the founder of Punk Design, where he leads projects that ignite Innovation Culture and equips teams to overcome Friction through bold, Human-Centred strategies. An expert in Design Thinking, Enrique
- [Suzie Miller](https://www.premstem.eu/2025/02/10/suzie-miller/) - Suzie Miller Professor Suzie MillerDirector, The Ritchie CentreMonash University and Hudson Institute of Medical Research (Australia) Session: Using large animal translational models and how to do it better - Wednesday 14 May (8.30-10am) Suzie Miller was appointed Director of The Ritchie Centre in 2022 and she holds a National Health and Medical Research Council of
- [Sandrine Thuret](https://www.premstem.eu/2025/02/17/sandrine-thuret/) - Sandrine Thuret Professor Sandrine ThuretProfessor of NeuroscienceHead Neurogenesis and Mental Health Laboratory; co-Head Basic and Clinical Neuroscience Department; co-Director Wellcome KCL PhD Programme in Mental Health Research for Health Professionals; Director MRC DTP in Biomedical Sciences; Co-Director King’s Institute for Human and Synthetic Minds, King’s College London (UK) Session: In vitro studies of stem cell
- [Richard Schäfer](https://www.premstem.eu/2025/02/21/richard-schafer/) - Richard Schäfer Professor Richard SchäferMedical Director Transfusion Medicine, Deputy Director Institute for Transfusion Medicine and Gene Therapy, Head Freiburg iPS CoreMedical Center, University of Freiburg (Germany) Session: In vitro studies of stem cell activities - Thursday 15 May (10.30am-12pm) Richard Schäfer is the Medical Director Transfusion Medicine at the Institute of Transfusion Medicine and Gene
- [António Salgado](https://www.premstem.eu/2025/02/13/antonio-salgado/) - António Salgado Dr António SalgadoCoordinating Investigator and Vice-Dean for ResearchLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho (Portugal) Session: Alternatives and adjuncts to stem cells - Wednesday 14 May (3.30-5pm) António Salgado is a biologist with a PhD in Tissue Engineering and Hybrid Materials (2005), and a Habilitation (DSc) in
- [Alishia Ballintine](https://www.premstem.eu/2025/03/24/alishia-ballintine/) - Alishia Ballintine Alishia BallintinePatient/parent representative (Australia) Session: Learnings from co-creation: involving external stakeholders in research - Thursday 15 May (8.30-10am​) Alishia Ballintine is a passionate patient and consumer advocate committed to advancing patient partnerships in medical development. Her advocacy is deeply personal, driven by her youngest daughter’s experience as a late preterm baby who suffered
- [Sidhartha Tan](https://www.premstem.eu/2025/03/21/sidhartha-tan/) - Sidhartha Tan Dr Sidhartha TanProfessor of PediatricsWayne State University (USA) Session: Novel and innovative approaches to screening - Tuesday 13 May (2-3.30pm) Dr Sidhartha Tan is presently Leslie Helppie Endowed Professor in Urban Health, Department of Pediatrics, Wayne State University School of Medicine. His research focuses on Big Data analytics in neonatal intensive care, advanced
- [Gaurav Verma](https://www.premstem.eu/2025/03/13/gaurav-verma/) - Gaurav Verma Dr Gaurav VermaResearcherUniversity of Gothenburg (Sweden) Session: In vitro studies of stem cell activities - Thursday 15 May (10.30am-12pm) Gaurav Verma is a passionate researcher specialising in mitochondrial biology and bioenergetics, with a focus on mitochondrial function in neurological disorders. Gaurav's current work explores mitochondrial transplantation in brain injury models, investigating how transplanted
- [Researchers to showcase research into neonatal brain repair at the PREMSTEM Conference](https://www.premstem.eu/2025/03/13/premstem-conference-announcement/) - The brain injury in the premature born infant: stem cell regeneration research network (PREMSTEM) is holding its final conference from 13 to 15 May 2025. The meeting will take place in Hotel SB Diagonal Zero in the Poblenou area of Barcelona, Spain. Since 2020, PREMSTEM has been focused on investigating human mesenchymal stem cells from
- [Nicolas Zucker](https://www.premstem.eu/2025/03/11/nicolas-zucker/) - Nicolas Zucker Nicolas ZuckerPhD student Physics for Medicine Paris (France) Session: Imaging modalities - Thursday 15 May (12.30-2pm) Nicolas Zucker is a PhD student in physics working on ultrasound neuroimaging. During his PhD he is exploring how functional ultrasound localisation microscopy can detect and quantify hemodynamic response at the microscopic scale. From preclinical to clinical
- [Gert van Steenbrugge](https://www.premstem.eu/2025/03/06/gert-van-steenbrugge/) - Gert van Steenbrugge Gert van SteenbruggePatient/parent representative (volunteer)Care4Neo (The Netherlands) Session: Learnings from co-creation: involving external stakeholders in research - Thursday 15 May (8.30-10am​) Gert van Steenbrugge is father of two preterm children, born respectively at 34 and 26 weeks of pregnancy. He is former director of the Dutch parent organisation VOC (currently known as
- [Sara De Palma](https://www.premstem.eu/2025/03/11/sara-de-palma/) - Sara De Palma Sara De PalmaPhD candidateDepartment for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children’s Hospital, Utrecht University, Utrecht (The Netherlands) Session: From pre-clinical work to an approved therapy - Wednesday 14 May (10.30am-12pm​) Sara De Palma studied at the Polytechnic University of Turin, completing both a bachelor's and
- [Umbilical cord-mesenchymal stem cells induce a memory phenotype in CD4+ T cells](https://www.premstem.eu/2025/03/07/umbilical-cord-mesenchymal-stem-cells/) - Ezgi Sengun, Tim G. A. M. Wolfs, Valéry L. E. van Bruggen, Bram van Cranenbroek, Elles R. Simonetti, Daan Ophelders, Marien I. de Jonge, Irma Joosten, Renate G. van der Molen
- [Pierre Gressens](https://www.premstem.eu/2025/02/28/pierre-gressens/) - Pierre Gressens Pierre GressensDirector, INSERM–Université Paris Cité laboratory U1141 (France) and PREMSTEM coordinator Session: Opening address - Tuesday 13 May (1.45-2pm) Pierre Gressens received his MD (UCL, Brussels, Belgium) in 1989 and his PhD at UCL in 1995. He specialised in Child Neurology and carried out his post-doctoral research training at NIH (Bethesda, USA). He
- [Lívia Nagy Bonnard](https://www.premstem.eu/2025/02/26/livia-nagy-bonnard/) - Lívia Nagy Bonnard Lívia Nagy Bonnard Patient Expert, EUPATI FellowRight(s) Beside You Association – Melletted a helyem Egyesület (Hungary) Session: Opening address - Tuesday 13 May (1.45-2pm) Lívia Nagy Bonnard is the Founder and Vice-President of the Melletted a Helyem Egyesület association for preterm babies in Hungary. She is the mother of four, including a
- [James Boardman](https://www.premstem.eu/2025/02/21/james-boardman/) - James Boardman Professor James BoardmanProfessor of Neonatal MedicineUniversity of Edinburgh (UK) Session: Imaging modalities - Thursday 15 May (12.30-2pm) James Boardman is Professor of Neonatal Medicine and Director of the Jennifer Brown Research Laboratory at the University of Edinburgh. He researches new ways of reducing brain injury and restoring learning potential after adverse early life
- [Máximo Vento](https://www.premstem.eu/2025/02/13/maximo-vento/) - Dr Máximo Vento Dr Máximo VentoEmeritus ResearcherInstituto de Investigación Sanitaria La Fe (IISLAFE), Valencia (Spain) Session: From pre-clinical work to an approved therapy - Wednesday 14 May (10.30am-12pm) • MD, PhD• Professor of Pediatrics• Division of Neonatology, Univ and Polytech Hospital La Fe, Valencia• 475 publications; h-index 73• Oxygen metabolism and redox regulation in neonatology:
- [End of year message from the PREMSTEM coordinator](https://www.premstem.eu/2024/12/18/end-of-2024/) - Once again, a busy year for PREMSTEM with progress made across all scientific work packages as well as an acceleration in the dissemination of our results through new publications and conference talks. Furthermore, planning is underway for our own conference in May 2025. This year, the European Commission approved an extension of PREMSTEM until the
- [PhD candidates and postdoc researchers present at the 2024 PREMSTEM annual meeting](https://www.premstem.eu/2024/07/19/young-investigators-2024/) - On 11 June 2024 in Gothenburg, PREMSTEM's young investigators presented their latest research to other members of the consortium. This session has become a tradition at the project's annual in person meeting following similar session in 2022 and 2023. This year's presenters were: Lotte Smeets, PhD candidate at Maastricht University: Biodistribution of MSCs after intravenous
- [2024 Annual meeting](https://www.premstem.eu/2024/07/16/annual-meeting-2024/) - The PREMSTEM team met in Gothenburg on 10 and 11 June 2024 for the annual in person meeting and Young Investigator Session. Thank you to Henrik Hagberg from the University of Gothenburg for his hard work to host the PREMSTEM consortium in Sweden while also organising the biannual Hershey Conference on Developmental Brain Injury that
- [Our co-creation journey comes to an end](https://www.premstem.eu/2024/02/27/co-creation-workshop-10/) - In our final workshop, we co-designed solutions to two more issues which came up in interviews with parents
- [PREMSTEM meeting February 2024](https://www.premstem.eu/2024/02/14/meeting-february-2024/) - In our first consortium online meeting of 2024 we discussed scientific progress and future planning
- [Introducing Lotte Smeets](https://www.premstem.eu/2024/02/14/lotte-smeets/) - Lotte is a PhD student at the MERLN Institute and the Department of Paediatrics at Maastricht University
- [Introducing Valéry van Bruggen](https://www.premstem.eu/2023/11/17/valery-van-bruggen/) - Valéry is a PhD student at the University of Maastricht working with Professor Tim Wolfs and Assistant Professor Daan Ophelders
- [Co-creating the final steps of the roadmap](https://www.premstem.eu/2024/01/31/co-creation-workshop-9/) - The roadmap prototype aims to improve the clinical trials experience for families
- [End of year message](https://www.premstem.eu/2023/12/14/end-of-2023/) - It’s been another busy year for the PREMSTEM team in which we also had our first project review meeting with European Commission representatives and external reviewers. We received positive feedback and comments related to how the project is progressing. To wrap things up for 2023, I’m happy to provide a short summary of some of
- [Final co-creation workshop of 2023](https://www.premstem.eu/2023/12/05/co-creation-workshop-8/) - In this workshop we popped on our magical hats and continued to co-design a parent journey roadmap to aid communications and improve the experience of a clinical trial.
- [PREMSTEM's young investigators present their research at the 2022 annual meeting](https://www.premstem.eu/2022/09/15/young-investigators-2022/) - The session was an opportunity to hear about the different PhD and postdoctoral research taking place among our partners
- [Young investigators present their research at the 2023 PREMSTEM annual meeting](https://www.premstem.eu/2023/09/29/young-investigators-2023/) - PhD and postdoctoral researchers presented their latest research to the PREMSTEM consortium
- [Introducing Silke Mader](https://www.premstem.eu/2020/06/24/silke-mader/) - As a result of her first-hand experience of preterm birth, Silke established the European Foundation for the Care of Newborn Infants to make heard the voices of parents of preterm and sick newborn infants
- [Introducing Hannah Tribe](https://www.premstem.eu/2020/08/19/hannah-tribe/) - Hannah is from the communications team at RMIT Europe and works with all partners in the PREMSTEM consortium to promote the project
- [Introducing Aisling Walsh](https://www.premstem.eu/2020/09/02/aisling-walsh/) - Aisling is Senior Project Manager at the European Foundation for the Care of Newborn Infants and proud of its work in advancing healthcare and support for newborns and their families worldwide
- [Introducing Ezgi Şengün](https://www.premstem.eu/2020/09/23/ezgi-sengun/) - Ezgi is a PhD student in the Laboratory of Medical Immunology at Radboudumc working with Professor Irma Joosten and Doctor Renate van der Molen
- [Co-creating the parent journey](https://www.premstem.eu/2023/11/10/co-creation-workshop-7/) - In this session we began building a parent journey roadmap, taking into account interview insights.
- [Insights from co-creation interviews](https://www.premstem.eu/2023/10/27/co-creation-workshop-6/) - In 2023 we have been learning more about clinical trial experiences through interviews with key stakeholders.
- [2023 Annual meeting](https://www.premstem.eu/2023/10/04/annual-meeting-2023/) - PREMSTEM consortium members came together for the project's annual meeting on 6 and 7 September 2023 at the Maastricht Exhibition and Conference Centre. We were also joined virtually by members of our advisory board. Maastricht University researchers organised the two-day programme which included a session for PhD and postdoctoral researchers to present their research, the
- [End of year message](https://www.premstem.eu/2022/12/09/end-of-2022/) - PREMSTEM project coordinator, Professor Pierre Gressens, reflects on our progress and activities in 2022
- [Why should women get into science?](https://www.premstem.eu/2023/02/09/idwgs-2023/) - To celebrate the 2023 International Day of Women and Girls in Science we asked some of our researchers about their science journey
- [A Parent’s Embrace: a powerful therapy](https://www.premstem.eu/2022/11/17/wpd-2022/) - This year’s World Prematurity Day theme is all about promoting the benefits of skin-to-skin contact between parents and baby from day one
- [Using co-creation to prepare for stakeholder interviews](https://www.premstem.eu/2022/11/03/co-creation-workshop-5/) - We're already halfway through our co-creation workshops and getting ready to interview stakeholders on a one-on-one basis
- [Cake tins, plants and a dinosaur – playing with household objects to tackle our co-creation challenge](https://www.premstem.eu/2022/10/03/co-creation-workshop-4/) - Imagination and storytelling were the name of the game in our latest workshop
- [2022 Annual meeting](https://www.premstem.eu/2022/09/16/annual-meeting-2022/) - PREMSTEM partners from different parts of Europe and Australia attended the project's first fully in-person meeting
- [Mesenchymal Stromal Cell-Derived Extracellular Vesicles Reduce Neuroinflammation, Promote Neural Cell Proliferation and Improve Oligodendrocyte Maturation in Neonatal Hypoxic-Ischemic Brain Injury](https://www.premstem.eu/2022/08/05/extracellular-vesicles/) - Nicole Kaminski, Christian Köster, Yanis Mouloud, Verena Börger, Ursula Felderhoff-Müser, Ivo Bendix, Bernd Giebel and Josephine Herz
- [Defining the outcomes to achieve in response to the co-creation challenge](https://www.premstem.eu/2022/07/27/co-creation-workshop-3/) - Creating one-liner statements and writing newspaper headlines were some of the activities in our latest co-creation workshop.
- [Refining PREMSTEM’s key stakeholders: the conversation continues](https://www.premstem.eu/2022/07/07/co-creation-workshop-2/) - In our second co-creation session, new and returning participants brought new perspectives to the table as we built on the discussions from the previous month
- [Defining our key stakeholders: Getting started with co-creation](https://www.premstem.eu/2022/06/07/co-creation-workshop-1/) - A group representing parents, clinicians and researchers has participated in PREMSTEM's first co-creation workshop
- [A lifeline for premature born babies: Funding announced for new stem cell research](https://www.premstem.eu/2020/05/06/funding-for-new-stem-cell-research/) - A group of researchers from across the globe is developing a new stem cell therapy to regenerate the brain damage caused by premature birth
- [2021 Annual meeting](https://www.premstem.eu/2021/10/04/annual-meeting-2021/) - The hybrid event took place on 28 September 2021 with partners attending both online and in person
- [PREMSTEM meeting May 2022](https://www.premstem.eu/2022/05/05/meeting-may-2022/) - Our first consortium meeting of 2022 was an opportunity to discuss the latest updates from our labs and to plan our annual meeting
- [A Model of Germinal Matrix Hemorrhage in Preterm Rat Pups](https://www.premstem.eu/2022/04/26/germinal-matrix-hemorrhage/) - Masako Jinnai, Gabriella Koning, Gagandeep Singh-Mallah, Andrea Jonsdotter, Anna-Lena Leverin, Pernilla Svedin, Syam Nair, Satoru Takeda, Xiaoyang Wang, Carina Mallard, Carl Joakim Ek, Eridan Rocha-Ferreira, Henrik Hagberg
- [What's great about being a scientist?](https://www.premstem.eu/2022/02/09/idwgs-2022/) - 11 February is the International Day of Women and Girls in Science. To celebrate this day, we asked some of the PREMSTEM team why they like working in science!
- [Doctor Cindy Bokobza awarded the 2021 Harmonie Mutuelle Alzheimer Prize](https://www.premstem.eu/2021/10/01/harmonie-mutuelle-reward/) - The PREMSTEM researcher was rewarded for her original approach to neurodegenerative diseases
- [End of year message](https://www.premstem.eu/2021/12/01/end-of-2021/) - PREMSTEM Project Coordinator, Professor Pierre Gressens, reflects on our progress and activities in 2021
- [Raising awareness and funds for cerebral palsy](https://www.premstem.eu/2021/10/04/steptember-2021/) - The PREMSTEM team has been getting active for STEPtember.
- [Celebrating the International Day of Women and Girls in Science 2021](https://www.premstem.eu/2021/02/10/women-in-science-2021/) - Implemented by UNESCO, this day is celebrated every year on 11 February to promote women and girls in science, and promote full and equal access to, and participation in, science for women and girls. To mark the day, we asked two of PREMSTEM's female researchers for their reflections of being a woman undertaking a career in science.
- [Introducing Doctor Daan Ophelders](https://www.premstem.eu/2020/11/25/daan-ophelders/) - Daan coordinates the large animal work carried out by the Department of Pediatrics at Maastricht University, including unique longitudinal studies in which consequences of perinatal inflammatory stress are assessed prenatally until adulthood
- [Raising money for people living with cerebral palsy](https://www.premstem.eu/2020/11/06/steptember-2020/) - This September, the PREMSTEM team participated in STEPtember to raise money for a good cause
- [Introducing Doctor Ivo Bendix](https://www.premstem.eu/2020/09/16/ivo-bendix/) - A researcher at Universitätsklinikum Essen, Ivo is looking at improving the understanding of the cellular and molecular mechanisms underlying neonatal white matter injury and evaluating potential new therapies in relevant experimental models
- [Introducing Doctor Megan Finch-Edmondson](https://www.premstem.eu/2020/09/09/megan-finch-edmondson/) - Megan is a research fellow at the Cerebral Palsy Alliance, building capacity for stem cell research for cerebral palsy by securing funding, conducting research, facilitating research collaboration, and leading consumer engagement
- [Introducing Doctor Cindy Bokobza](https://www.premstem.eu/2020/08/26/cindy-bokobza/) - Cindy received her PhD in neuroscience in 2019 and is now a postdoctoral research scientist in the lab of NeuroDiderot-Gressens in Paris
- [Introducing Doctor Caroline de Theije](https://www.premstem.eu/2020/08/12/caroline-de-theije/) - A researcher at University Medical Center Utrecht, Caroline is interested in the optimisation of stem cell-based therapies and collaborates with industry partners on nutritional therapies for neonatal brain injury
- [Introducing Professor Luc Zimmermann](https://www.premstem.eu/2020/08/05/luc-zimmermann/) - A widely recognised paediatrician and neonatologist, Luc contributes to the strategic direction of the European Foundation for the Care of Newborn Infants and its mission to reduce the health and social inequalities linked to preterm birth
- [Introducing Doctor Katiuscia Dallaglio](https://www.premstem.eu/2020/07/29/katiuscia-dallaglio/) - Katiuscia is R&D project leader of advanced therapies in rare diseases at Chiesi Group, an Italian research-based pharmaceutical company
- [Introducing Doctor Yohan van de Looij](https://www.premstem.eu/2020/07/22/yohan-van-de-looij/) - Yohan is a physicist at the Université de Genève with extensive experience in the study of animal models of perinatal brain injuries using magnetic resonance imaging (MRI) and spectroscopy
- [Introducing Doctor Johanna Kostenzer](https://www.premstem.eu/2020/07/15/johanna-kostenzer/) - Johanna from the European Foundation for the Care of Newborn Infants is experienced in international and multi-site research projects and has been active in the public health and nonprofit sector
- [Introducing Doctor Bobbi Fleiss](https://www.premstem.eu/2020/06/16/bobbi-fleiss/) - A researcher at RMIT University, Bobbi's particular focus is on the role of inflammation in injury to the preterm infant brain and strategies to facilitate repair and support regeneration
- [Introducing Doctor Tessa Goes-Roelofs](https://www.premstem.eu/2020/07/08/tessa-goes-roelofs/) - A researcher at University Medical Center Utrecht, Tessa is building on her background in translational neuroscience to research how stem cells can repair brain damage in preterm infants
- [Introducing Doctor Syam Nair](https://www.premstem.eu/2020/07/01/syam-nair/) - Syam is an early career researcher in the field of mitochondrial biology and neonatal brain injury at the University of Gothenburg

## Pages

- [PREMSTEM homepage](https://www.premstem.eu/) - About the project premstem PREMSTEM is a €9M research project funded by the European Union’s prestigious Horizon 2020 research and innovation programme. We are a group of researchers from across the globe developing a new regenerative stem cell therapy to repair the brain damage caused by premature birth, also known as encephalopathy of prematurity (EOP).
- [Publications](https://www.premstem.eu/publications/) - News and publications publications The below publications include a funding acknowledgement to the project. PREMSTEM researchers are highlighted as bold. Check out our research highlights page to find summaries of selected papers. List of publications Progress in cell therapies for neonatal conditions: Proceedings of the Third Neonatal Cell Therapies Symposium (2025)Abdul Razak, Suzanne L. Miller, Courtney
- [Resources](https://www.premstem.eu/resources/) - Resources Videos, fact sheets and illustrated story Videos Playlist 7 Videos PREMSTEM project video 2:16 Stem cells: What are they and what can they do? 2:36 ¿Qué son las células madre y qué funciones cumplen? 2:36 Was sind Stammzellen und welche Funktion haben sie? 2:36 Mik azok az őssejtek és honnan származnak? 2:36 Que sont
- [All about the brain](https://www.premstem.eu/about-the-brain/) - Our research explained About the brain PREMSTEM research and the brain Many of PREMSTEM’s researchers are experts in disorders related to the brain, such as cerebral palsy, and together bring years of experience studying different types of brain injury to the project. As a team, we’re trying to find a new therapy to reduce the
- [Neonatal encephalopathy](https://www.premstem.eu/neonatal-encephalopathy/) - Our research explained Neonatal encephalopathy What is neonatal encephalopathy? What triggers it? Encephalopathy means damage or injury to the brain. When it happens to a newborn baby, we call it neonatal encephalopathy. There are a few types of encephalopathy, including hypoxic-ischemic encephalopathy which occurs when a baby doesn’t get enough oxygen or blood supply during
- [PREMSTEM Conference 2025](https://www.premstem.eu/premstem-conference-2025/) - Information on this page About the PREMSTEM Conference We are pleased to announce that the PREMSTEM Conference will take place in Barcelona from 13 to 15 May 2025. We invite internal and external stakeholders to join us as we present results from our scientific endeavours and their potential benefit to society. Hear about the next
- [Research activity overview](https://www.premstem.eu/research-overview/) - about premstem research activity overview timeline project activities PREMSTEM is a research project in the field of regenerative medicine which has received funding from the European Union’s Horizon 2020 research and innovation programme. The following is an overview of our planned activities:The efficiency of a given therapy heavily depends upon its delivery modalities. Our first
- [Latest news](https://www.premstem.eu/news/) - news and publications latest news news stories and interviews News PREMSTEM research lays the groundwork for future stem cell clinical trials Read the story News Illustrating two families’ stories of preterm birth Read the story News Global experts converge in Barcelona for the PREMSTEM Conference: Research into neonatal brain repair Read the story News 2025
- [Research highlights](https://www.premstem.eu/research-highlights/) - News and publications Research highlights Summaries of PREMSTEM publications To learn more about our research findings without reading the full scientific paper, take a look at our research highlights! Our highlights aim to summarise the key aims and outcomes of investigations related to the PREMSTEM project so you can get to know more about what
- [Why is this research important?](https://www.premstem.eu/research-importance/) - our research explained why is this research important? Project overview The brain injury in the premature born infant: stem cell regeneration research network (PREMSTEM) is a global team focused on delivering a novel regenerative therapy to reduce the enormous emotional and economic implication of neurodevelopmental injury caused by brain damage associated with premature birth.There are
- [Preterm birth](https://www.premstem.eu/preterm-birth/) - Our research explained Preterm birth Overview Being born early disrupts important developmental and growth processes taking place during the pregnancy. The 37th week of pregnancy, approximately the 9-month mark, is the time at which we say a baby is ‘full term’. A term baby has been through all stages of growth and development expected to occur
- [Research partners](https://www.premstem.eu/partners/) - our team research partners PREMSTEM is a global team of world leading clinicians, researchers, stakeholder advocacy groups and an industrial partner with well-established experience in neonatology and drug development. Research team profiles
- [Co-creation activities](https://www.premstem.eu/co-creation-activities/) - Co-creation Stakeholder engagement in the PREMSTEM project What is co-creation? Co-creation is a method which allows the involvement of various stakeholder groups, for example of a service or product, to work with a company on an idea or concept. Co-creation can help people involved in a project to see beyond their own perspectives by letting external
- [Research team profiles](https://www.premstem.eu/profiles/) - our team research team profiles Read the interviewREAD THE INTERVIEWRead the interviewRead the interviewRead the interviewRead the interviewRead the interviewRead the interviewread the interviewRead the interviewRead the interviewRead the interviewRead the interviewread the interviewRead the interviewRead the interviewRead the interviewRead the interview research partners PATIENT/CONSUMER ADVISORY BOARD
- [Related projects](https://www.premstem.eu/related-projects/) - About PREMSTEM Related projects PREMSTEM is funded by the European Union’s Horizon 2020 research and innovation programme under the call for Better Health and care, economic growth and sustainable health systems (H2020-SC1-BHC-2018-2020). Our sister projects are those who were funded in the same call. We’re connected by our joint aim of developing therapies and treatments
- [Health risks related to preterm birth](https://www.premstem.eu/health-risks-preterm-birth/) - Our research explained Health risks related to preterm birth overview A baby born before completing 37 weeks of gestation is described as having been born preterm or prematurely. A preterm birth disrupts important developmental and growth processes which take place during the pregnancy in utero. Babies born preterm are at a greater risk for various
- [About stem cells](https://www.premstem.eu/about-stem-cells/) - Our research explained What are stem cells and why are they used in research? What are stem cells? PREMSTEM aims to validate the use of stem cells as a regenerative therapy for brain injury related to being born preterm. To ‘rebuild’ the damaged areas of the brain, our scientists are using human mesenchymal stem cells
- [Frequently asked questions](https://www.premstem.eu/faqs/) - our research explained Frequently asked questions what is preterm birth? Premature or preterm birth is generally defined as one occurring before 37 of 40 weeks of gestation, but did you know there are actually three sub-categories? 'extremely preterm' means the baby is born before 28 weeks of gestation more than 50% of babies who survive
- [Animal models](https://www.premstem.eu/animal-models/) - Our research explained Why do we use animals in our research? overview Babies born preterm are extremely fragile because many of their body functions and vital organs are not yet sufficiently developed. As a result of preterm birth, they often develop brain damage which can affect the way that they think, learn or move throughout
- [Our expertise](https://www.premstem.eu/expertise/) - our research explained our expertise team overview The PREMSTEM team is a collective of world leading clinicians, researchers, stakeholder advocacy groups and an industrial partner with well-established experience in neonatology and drug development. Our fifteen research partners represent eight countries: Australia, France, Germany, Italy, The Netherlands, Spain, Sweden and Switzerland. our expertise The researchers in
- [Ethics of stem cells  ](https://www.premstem.eu/ethics-of-stem-cells/) - Our research explained Ethics of stem cells Do you need ethical approval to do stem cell research? Research involving stem cells like human mesenchymal stem cells (H-MSCs) is highly regulated. PREMSTEM’s stem cells come with the informed consent from the donor for research use only. The company who produce H-MSCs from umbilical cord tissue sought ethical
- [Research team](https://www.premstem.eu/research-team/) - about premstem research team overview Driving innovative and high-quality researchDesigning novel technological solutions to clinical needsEngaging stakeholders in the design, implementation and outcomes of our researchNavigating the complex regulatory frameworks for designing a neonatal therapyOur researchers have vast experience in studying the mechanisms of perinatal brain injury and neurotherapeutic testing as evidenced by the hundreds
- [Privacy](https://www.premstem.eu/privacy/) - premstem privacy who we are Our website address is https://www.premstem.eu. Site ownership This website is owned by RMIT University and managed by RMIT Europe. Privacy Statement This website is covered by the RMIT Privacy Statement. RMIT values the privacy of every individual and is committed to the responsible handling of personal information. This Privacy Statement explains what
- [Call for co-creation facilitator](https://www.premstem.eu/call-for-facilitator/) - co-creation premstem is seeking to appoint a co-creation facilitator background PREMSTEM aims to take its stem cell therapy to clinical trial. Through co-creation activities, we aim to engage our stakeholders early on and throughout the project. Given their differing personal and professional experiences and circumstances, their participation and contributions will provide a range of distinct perspectives
- [Expected impacts](https://www.premstem.eu/expected-impacts/) - about premstem expected impacts overview Research into infants is an underfinanced and underrepresented area. PREMSTEM will advance this field of research for the benefit of individual families and the entire community. overview PREMSTEM provides a unique opportunity to have engaged stakeholder, clinical and industry support assuring research will be translated into effective clinical trials. overview
- [Project summary](https://www.premstem.eu/project-summary/) - about premstem project summary overview The brain injury in the premature born infant: stem cell regeneration research network, PREMSTEM, is a collective of world leading clinicians, researchers, stakeholder advocacy groups and an industrial partner with well-established experience in neonatology and drug development.PREMSTEM is focused on delivering to the clinic a novel regenerative therapy to reduce the
- [Connect with us](https://www.premstem.eu/connect/) - connect with us keep in touch contact us If you have a question about the PREMSTEM project, submit your query via the contact form. This website is covered by the RMIT Privacy Statement which details how personal information is used, processed, stored and disclosed. Please enable JavaScript in your browser to complete this form.Name *FirstLastEmail
- [Cookies](https://www.premstem.eu/cookies/) - About cookies This page explains what cookies are and how we use them, the types of cookies we use i.e, the information we collect using cookies and how that information is used, and how to control the cookie preferences. You can at any time change or withdraw your consent from the Cookie Declaration on our
- [Patient/Consumer Advisory Board](https://www.premstem.eu/pcab/) - our team Patient/Consumer Advisory Board Patient/Consumer Advisory Board overview The PREMSTEM project has the potential to have a big impact on society and we want to make sure that we communicate our research progress and findings to as many interested people as possible. To help us do so, we have established an independent consultative group

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- [Stem cell videos](https://www.premstem.eu/?elementor_library=stem-cell-videos) - Playlist 3 Videos Stem cells: What are they and what can they do? 2:36 ¿Qué son las células madre y qué funciones cumplen? 2:36 Was sind Stammzellen und welche Funktion haben sie? 2:36 Visit the Cerebral Palsy Alliance website to learn more in their Science Behind Stem Cells and Brain Injury video series.
- [PREMSTEM news post](https://www.premstem.eu/?elementor_library=premstem-post) - news 6 May 2020 The PREMSTEM project has received €9M in funding to research a new therapy to treat brain damage associated with preterm birth, also known as encephalopathy of prematurity (EoP). To ‘rebuild’ the damaged areas of the brain, scientists will use human mesenchymal stem cells (H-MSCs) – those taken from umbilical cord tissue
- [Research highlights](https://www.premstem.eu/?elementor_library=elementor-single-post-3334) - Research highlights Research highlights premstem authors on this paper: Download the research highlights Every year, around 15 million babies worldwide are born before 37 weeks of gestation. Being born preterm can disrupt development, and earlier births increase the risk of life-changing health outcomes. There are currently no treatment options for brain injury that occurs because of preterm birth, but progress has been
- [Posts grid](https://www.premstem.eu/?elementor_library=posts-grid) - News PREMSTEM research lays the groundwork for future stem cell clinical trials The PREMSTEM project has explored how human mesenchymal stem cells could help to repair brain injury in children born preterm. Read more News Illustrating two families’ stories of preterm birth News Global experts converge in Barcelona for the PREMSTEM Conference: Research into neonatal
- [PREMSTEM interview (academic)](https://www.premstem.eu/?elementor_library=premstem-interview-academic) - interview 8 May 2020 What is your area of research specialism and what attracted you to it? Brain damage occurring around the time of birth causes death and disability in many millions of babies every year. Understanding the causes of brain injury and designing therapies is the focus of my work. My high school science
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- [PREMSTEM flip box](https://www.premstem.eu/?elementor_library=premstem-flip-box) - 'extremely preterm' means the baby is born before 28 weeks of gestation more than 50% of babies who survive being born ‘extremely preterm’ will suffer lifelong disability
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- [PREMSTEM page](https://www.premstem.eu/?elementor_library=premstem-page) - about premstem project summary overview The brain injury in the premature born infant: stem cell regeneration research network, PREMSTEM, is a collective of world leading clinicians, researchers, stakeholder advocacy groups and an industrial partner with well-established experience in neonatology and drug development. PREMSTEM is focussed on delivering to the clinic a novel regenerative therapy to reduce
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## Categories

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## Tags

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